BaHSic Lab

BaHSic — Blood group Antigens, Hematopoiesis and Sickle cell disease

Hematopoiesis & Translational Research: blood cell biology, multi-omic approaches, and translational studies.

Contact (+33) 1 81 72 43 14 sara.bencheikh@inserm.fr

Location Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

Axel Joly

Postdoctoral researcher

UMR_S1134 (BIGR) Inserm– BAHSic Lab

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Dr JOLY did his PhD in the Sandrina KINET’s Team in Montpellier laboratory working on the metabolic regulation of erythropoiesis. His research focuses on the role of cysteine uptake and metabolism in the regulation of protein translation process in erythroid progenitors.

Research interests

  • Erythropoiesis and red blood cell biology
  • Metabolism
  • Hematopoietic stem and progenitor cells
  • Sickle cell disease/DBA

Key expertise

  • Primary HSC culture
  • Flow cytometry
  • Metabolic assays

Background

  • PhD in Biology – University of Montpellier (2025)
  • PharmD – University of Montpellier (2023)
  • MSc in Regenerative Medicine – University of Montpellier (2021)

Current projects

Investigating the role of metabolic genes in the regulation of HbF expression using drug screening, genetic approaches, functional and metabolic assays.

Personal interests

  • History
  • Opera/Classical music
🩸 Red blood cells 🔥 Inflammation 🧬 Blood group antigens 🧫 Sickle Cell Disease 🌱 Hematopoiesis 🛡️ Spleen Alloimmunization 🧬🔬 CRISPR-Cas9 • scRNA-seq • Proteomics • Microfluidics • Amnis • Rheology • ATAC-seq 🧫 Erythroid cell lines 🧪 Immunohematology
Inserm BaHSic UPC EFS U_Antilles
Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

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