BaHSic Lab

BaHSic — Blood group Antigens, Hematopoiesis and Sickle cell disease

Hematopoiesis & Translational Research: blood cell biology, multi-omic approaches, and translational studies.

Contact (+33) 1 81 72 43 14 sara.bencheikh@inserm.fr

Location Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

Laetitia Claer

Research engineer

UMR_S1134 (BIGR) Inserm– BAHSic Lab

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Laetitia CLAER is a research engineer in the BaHSic laboratory. She is involved in multiple projects under Dr Sandrine LAURANCE supervision, especially on the study of the erythropoiesis disorders in sickle cell disease. She is also a flow cytometry expert and brings strong technical expertise in high-parameter flow cytometry and cell sorting.

Research interests

  • Erythropoiesis and red blood cell biology
  • Sickle cell disease
  • Hydroxyurea mechanism of action
  • Hematopoietic stem and progenitor cells

Key expertise

  • Multiparametric flow cytometry (analysis and sorting)
  • Cell culture of primary cells and cell lines
  • Molecular biology

Background

  • MSc in Infectious diseases – University of Claude Bernard Lyon 1 (2013)
  • BSc in Life Sciences – University of Claude Bernard Lyon 1 (2011)
  • DUT in Biology and Biochemistry – IUT A Lyon 1 (2010)

Current projects

Elucidating the mechanisms by which hydroxyurea modulates erythropoiesis in sickle cell disease through flow cytometry, molecular biology, and transcriptomics.

Personal interests

  • Music
  • Traveling
  • Reading
🩸 Red blood cells 🔥 Inflammation 🧬 Blood group antigens 🧫 Sickle Cell Disease 🌱 Hematopoiesis 🛡️ Spleen Alloimmunization 🧬🔬 CRISPR-Cas9 • scRNA-seq • Proteomics • Microfluidics • Amnis • Rheology • ATAC-seq 🧫 Erythroid cell lines 🧪 Immunohematology
Inserm BaHSic UPC EFS U_Antilles
Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

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