BaHSic Lab

BaHSic — Blood group Antigens, Hematopoiesis and Sickle cell disease

Hematopoiesis & Translational Research: blood cell biology, multi-omic approaches, and translational studies.

Contact (+33) 1 81 72 43 14 sara.bencheikh@inserm.fr

Location Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

Steven Akkaya

PhD student

UMR_S1134 (BIGR) Inserm– BAHSic Lab

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Steven Akkaya is a PhD student in the BAHSic laboratory, working on the maturation of the hematopoietic system in sickle cell disease. His research focuses on cellular and molecular alterations affecting hematopoiesis in neonates and children with sickle cell disease.

Research interests

  • Sickle cell disease
  • Hematopoietic stem and progenitor cells biology
  • Cord Blood/Spleen
  • Single-cell transcriptomics
  • Erythropoiesis and Myelopoiesis

Key expertise

  • Hematopoietic stem and progenitor cells biology
  • Cell culture
  • Flow cytometry
  • Cell sorting

Background

  • MSc in Genetics – University of Paris Cité (2023)
  • BSc in Life Sciences – University of Paris Cité (2021)

Current projects

Investigating the molecular landscape and functional capacities of cord blood and spleen derived Hematopoietic Stem and Progenitor cells (HSPCs) in children with sickle cell disease using single-cell transcriptomics and functional assays.

Personal interests

  • Hiking and outdoor activities
  • Cinema
  • Traveling
🩸 Red blood cells 🔥 Inflammation 🧬 Blood group antigens 🧫 Sickle Cell Disease 🌱 Hematopoiesis 🛡️ Spleen Alloimmunization 🧬🔬 CRISPR-Cas9 • scRNA-seq • Proteomics • Microfluidics • Amnis • Rheology • ATAC-seq 🧫 Erythroid cell lines 🧪 Immunohematology
Inserm BaHSic UPC EFS U_Antilles
Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

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