BaHSic Lab

BaHSic — Blood group Antigens, Hematopoiesis and Sickle cell disease

Hematopoiesis & Translational Research: blood cell biology, multi-omic approaches, and translational studies.

Contact (+33) 1 81 72 43 14 sara.bencheikh@inserm.fr

Location Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

Publications

Duval R, Soudry A, De Oliveira Rios J, Linguet SL, Taillepierre M, Matesic G, Raneri A, Laiguillon G, Le Toriellec E, Gautier EF, Vainqueur D, Babinet J, Masson C, Gelly JC, Le Van Kim C, Romana M, Chen D, Santoso S, Koehl B, Peyrard T, Azouzi S. The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes Csa/Csb red cell antigens. Blood. 2025 Mar 16:blood.2024026285. doi: 10.1182/blood.2024026285.
Koehl B, Vrignaud C, Mikdar M, Nair TS, Yang L, Landry S, Laiguillon G, Giroux- Lathuile C, Anselme-Martin S, El Kenz H, Hermine O, Mohandas N, Cartron JP, Colin Y, Detante O, Marlu R, Le Van Kim C, Carey TE, Azouzi S, Peyrard T. Lack of the human choline transporter-like protein SLC44A2 causes hearing impairment and a rare red blood phenotype. EMBO Mol Med. 2023 Mar 8;15(3):e16320. doi: 10.15252/emmm.202216320.
Mikdar M, Serra M, Colin E, Duval R, Gauthier EF, Lamarre Y, Colin Y, Le Van Kim C, Peyrard T, Koehl B, Azouzi S. Adenosine signaling inhibits erythropoiesis and promotes myeloid differentiation. Haematologica. 2024 Jan 1;109(1):175-185. doi: 10.3324/haematol.2022.281823.
Garnier Y, Ferdinand S, Garnier M, Cita KC, Hierso R, Claes A, Connes P, Hardy- Dessources MD, Lapouméroulie C, Lemonne N, Etienne-Julan M, El Nemer W, Romana M. Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties. Blood. 2020 Jul 9;136(2):247-256. doi: 10.1182/blood.2020004853.

🩸 Red blood cells 🔥 Inflammation 🧬 Blood group antigens 🧫 Sickle Cell Disease 🌱 Hematopoiesis 🛡️ Spleen Alloimmunization 🧬🔬 CRISPR-Cas9 • scRNA-seq • Proteomics • Microfluidics • Amnis • Rheology • ATAC-seq 🧫 Erythroid cell lines 🧪 Immunohematology

Contact

Hôpital Necker – Enfants Malades 149 rue de Sèvres 75015 Paris

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